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Related Concept Videos

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Related Experiment Video

Updated: Jul 19, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
03:26

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Sacral nerve stimulation for voiding dysfunction: One institution's 11-year experience.

Suzette E Sutherland1, Ann Lavers, Angeline Carlson

  • 1Metro Urology, Center for Continence Care and Female Urology, Minneapolis/St. Paul, Minnesota 55441, USA. sesutherlnd@aol.com

Neurourology and Urodynamics
|November 2, 2006
PubMed
Summary

Sacral neuromodulation (SNS) effectively treats refractory voiding dysfunction, improving symptoms like urinary urgency and frequency. While reportable events occurred, most were mild, and newer tined leads show reduced complication rates.

Related Experiment Videos

Last Updated: Jul 19, 2026

Detrusor Underactivity Model in Rats by Conus Medullaris Transection
03:26

Detrusor Underactivity Model in Rats by Conus Medullaris Transection

Published on: August 28, 2020

Area of Science:

  • Urology
  • Neuromodulation
  • Pelvic Floor Dysfunction

Background:

  • Refractory voiding dysfunction significantly impacts quality of life.
  • Sacral neuromodulation (SNS) offers a therapeutic option for complex cases.
  • The evolution of SNS technology, including lead types and implantation procedures, has occurred over time.

Purpose of the Study:

  • To review an 11-year institutional experience with sacral neuromodulation (SNS) for refractory voiding dysfunction.
  • To analyze the efficacy and safety of SNS across different technological phases.
  • To evaluate patient outcomes, including symptom improvement and device-related events.

Main Methods:

  • Retrospective review of 104 patients who received an implantable pulse generator (IPG) for SNS between 1993 and 2004.
  • Analysis of patient demographics, symptom duration, and pre- and post-implantation voiding parameters.
  • Assessment of subjective improvement, patient satisfaction, lead durability, and reportable events (REs).

Main Results:

  • Significant improvements in urinary urgency/frequency (U/F) and urge incontinence (UI) were observed post-SNS implantation (P < 0.05).
  • Sustained subjective improvement was reported by a majority of patients (>50% at >50% follow-up).
  • Tined leads demonstrated a lower reportable event rate (28%) compared to non-tined leads (73%).

Conclusions:

  • Sacral neuromodulation (SNS) is an effective treatment for specific voiding dysfunctions.
  • Despite a 53% reportable event rate, 97% were mild-to-moderate, not hindering therapy continuation.
  • Advancements in technology, particularly percutaneous tined leads, are associated with decreasing reportable event rates.