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Updated: Jul 19, 2026

Establishment and Evaluation of a Risk Prediction Model for Pathological Escalation of Gastric Low-Grade Intraepithelial Neoplasia
Published on: February 16, 2024
Metaplasia--a transdifferentiation process that facilitates cancer development: the model of gastric intestinal
Patrícia Mesquita1, Almeida Raquel, Lunet Nuno
1Institute of Molecular Pathology and Immunology (IPATIMUP), University of Porto, Portugal.
Abstract:
Metaplasia, in general, and intestinal metaplasia, in particular, are transdifferentiation processes triggered by environmental aggressions. The heterogeneity of different morphologic variants of metaplasia and distinction from close morphologic entities--heterotopia and hamartoma--is reviewed. Recent data on the characterization of the molecular and epidemiological data involved in the development and progression of lesions of gastric intestinal metaplasia are discussed. A redefinition of intestinal metaplasia is proposed.
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