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Published on: November 6, 2019
Preoperative screening for coagulation disorders in children undergoing adenoidectomy (AT) and tonsillectomy (TE):
S Eisert1, M Hovermann, H Bier
1Department of Pediatric Oncology, Hematology and Immunology, Children's University Hospital, Heinrich Heine University Düsseldorf. susanne.eisert@uni-duesseldorf.de
Insights
Preoperative coagulation screening in children undergoing adenotonsillectomy (AT) and/or tonsillectomy (TE) did not effectively identify those at risk for bleeding complications. Standard tests failed to predict major bleeding events in this pediatric surgical population.
Area of Science:
- Pediatric Surgery
- Hematology
- Otolaryngology
Background:
- Bleeding is a significant complication following adenotonsillectomy (AT) in children.
- Preoperative coagulation tests are commonly used to screen for bleeding disorders.
- The efficacy of these tests in preventing surgical bleeding remains under investigation.
Purpose of the Study:
- To evaluate the effectiveness of preoperative coagulation screening in identifying children at risk of bleeding complications from adenotonsillectomy (AT) and/or tonsillectomy (TE).
Main Methods:
- Prospective study of two groups of children undergoing AT/TE: one group with routine preoperative screening, and another with prolonged activated partial thromboplastin time (aPTT).
- Coagulation disorders were assessed via bleeding history and laboratory tests.
- Surgical bleeding events were retrospectively analyzed.
Main Results:
- Coagulation disorders were identified in 4.7% of children in the routine screening group and 12.1% in the prolonged aPTT group.
- Major bleeding occurred in 1 of 141 patients (0.7%) in the routine group and 4 of 79 patients (5.1%) in the prolonged aPTT group.
- Preoperative screening tests had zero sensitivity for detecting major bleeding in the routine screening group.
Conclusions:
- Current preoperative coagulation screening protocols are insufficient for predicting major bleeding in pediatric patients undergoing adenotonsillectomy and/or tonsillectomy.
- Further research is needed to develop more effective methods for identifying at-risk patients.
Background:
Bleeding remains the most important complication of adenotonsillectomy in children. Preoperative coagulation tests are widely used to detect unknown bleeding disorders. To determine the efficacy of preoperative coagulation screening in preventing bleeding complications.
Patients:
Study group 1: 148 healthy children referred by the otorhinolaryngology department for preoperative pediatric examination. Study group 2: 124 healthy children sent to the hemostaseologic clinic for preoperative investigation of a prolonged PTT.
Method:
The incidence of relevant coagulation disorders detected by a standardized bleeding history and coagulation screening tests was studied prospectively in 2 study groups planned for AT and/or TE. The frequency of abnormal bleeding was investigated retrospectively in those children who underwent surgery.
Results:
Bleeding disorders were detected in 7/148 and 15/124 children in study group 1 and 2 respectively. 141/148 and 79/124 children actually underwent surgery, 62 TE +/- AT + 79 AT alone and 26 TE +/- AT + 53 AT alone respectively. Major bleeding occurred in 1/141 patients (1 TE) in study group 1. Preoperatively, this child had shown normal coagulation screening tests. In 4/79 patients (3 TE, 1 AT) in study group 2, surgery was complicated by major bleeding. Despite extensive testing, no relevant bleeding disorder had been diagnosed in these children preoperatively. Sensitivity of coagulation screening tests for major bleeding was 0 in study group 1.
Conclusions:
In our study, coagulation screening failed to effectively identify patients at risk of bleeding.
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