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Published on: November 18, 2017
Toxicological effects of Carica papaya seed extract on spermatozoa of mice
R J Verma1, Deepa Nambiar, N J Chinoy
1Department of Zoology, University School of Sciences, Gujarat University, Ahmedabad-380009, India. ramtejverma2000@yahoo.com
Abstract:
Investigations were carried out on epididymal spermatozoa of male mice to study the effects of high dosages (100, 200 and 300 mg kg(-1) bwt) of aqueous Carica papaya seed extract. The results revealed a significant dosedependent suppression of cauda epididymal sperm motility coinciding with a decrease in sperm count and viability. When tested 45 days after the withdrawal of treatment, complete normalcy was restored, proving that the induced effects were transient.
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