[Role of gap junction in ischemic preconditioning].

De-chun Su1, Zhi-wen Chang, Shu-ying Fan

  • 1Department of Cardiology, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.

Summary

Ischemic preconditioning reduces heart attack size by activating mitochondrial ATP-sensitive potassium channels and altering connexin43. Blocking gap junctions did not affect this protective effect, suggesting they are not essential for preconditioning.

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