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Bilateral mandibular condylysis in a patient with systemic sclerosis
R G Jagger1, E G Absi, H G Jeremiah
1Division of Restorative Dentistry, Department of Oral and Dental Sciences, University of Bristol, Bristol BS1 2LY, UK. r.jagger@bristol.ac.uk
Dento Maxillo Facial Radiology
|November 4, 2006
Summary
Systemic sclerosis (SSc) can cause progressive osteolysis, a condition leading to bone loss, in the mandibular condyles. This case highlights orofacial manifestations and imaging findings associated with SSc.
Area of Science:
- Rheumatology
- Oral and Maxillofacial Surgery
- Radiology
Background:
- Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by fibrosis, vascular abnormalities, and immune dysregulation.
- Orofacial manifestations are common in SSc, affecting the skin, muscles, and bones of the head and neck.
- Progressive osteolysis of the mandibular condyles is a rare but significant complication.
Observation:
- A 55-year-old female patient with a diagnosis of systemic sclerosis presented with progressive osteolysis of the mandibular condyles.
- Clinical examination revealed orofacial signs consistent with SSc.
- Radiological imaging (e.g., CT scans, MRI) demonstrated significant bone resorption and structural changes in the mandibular condyles.
Findings:
- The case illustrates a direct correlation between systemic sclerosis and progressive osteolysis of the mandibular condyles.
- Radiological findings confirmed the extent of bone loss and its impact on mandibular anatomy.
- Discussion of the pathogenesis and clinical significance of this specific SSc manifestation.
Implications:
- Early recognition of orofacial symptoms in SSc patients is crucial for timely diagnosis and management.
- Understanding the radiological manifestations aids in monitoring disease progression and treatment efficacy.
- This case underscores the importance of a multidisciplinary approach involving rheumatologists and dental/maxillofacial specialists for comprehensive SSc patient care.
