Related Experiment Video
Updated: Jul 19, 2026

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
Published on: October 24, 2019
Technical development of PubMed interact: an improved interface for MEDLINE/PubMed searches
1Office of High Performance Computing and Communications, National Library of Medicine, 8600 Rockville Pike, Bethesda, Maryland 20894, USA. mmuin@mail.nih.gov
PubMed Interact offers an enhanced, interactive web interface for MEDLINE/PubMed searches, improving user experience for both novice and advanced users. This tool leverages advanced web technologies for efficient search parameter management and result handling.
Area of Science:
- Medical Informatics
- Biomedical Search Technology
Background:
- MEDLINE/PubMed search interfaces can be challenging for novice users.
- Previous versions, like SLIM, explored parameter control via JavaScript sliders.
- The need for enhanced user interactivity in medical literature searching is recognized.
Purpose of the Study:
- To develop an alternative, interactive search interface for MEDLINE/PubMed.
- To enhance user experience for both novice and advanced users of medical databases.
- To integrate recent web technologies for improved search functionality.
Main Methods:
- Developed PubMed Interact, a web-based application using HTML, JavaScript, and PHP.
- Utilized client-side scripting (JavaScript, DHTML, DOM manipulation, Ajax) for interactive features.
- Implemented a backend engine using PHP to connect with E-Utilities and parse XML data.
Main Results:
- PubMed Interact provides interactive features such as slider bars for search limits and instant preview of result counts.
- Users can manage search results by deleting citations, displaying related articles, and creating relevance lists.
- Client-side processing enables instant feedback, reducing the need for page reloads and enhancing efficiency.
Conclusions:
- PubMed Interact is a highly interactive web application for MEDLINE/PubMed searches.
- It effectively utilizes modern web technologies like DOM manipulation and Ajax.
- Represents a valuable advancement for online medical search applications.
Related Concept Videos
Protein-protein Interfaces
Protein-Protein Interfaces
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Genetic Screens
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Ligand Binding Sites
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
Structure-Activity Relationships and Drug Design
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence its...