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Multicentric intracranial fibrous xanthoma--case report
A Yamataki1, Y Chiba, K Tokoro
1Department of Neurosurgery, Kanagawa Rehabilitation Center, Japan.
Neurologia Medico-Chirurgica
|October 1, 1990
Summary
Intracranial fibrous xanthoma is a rare brain tumor. This case highlights its multicentric presentation and unique imaging features on MRI, aiding diagnosis.
Area of Science:
- Neurology
- Pathology
- Radiology
Background:
- Intracranial fibrous xanthoma is an exceptionally rare tumor, with only 11 cases previously documented.
- Accurate diagnosis is challenging due to its rarity and potential misdiagnosis as other intracranial lesions.
Observation:
- A case of multicentric intracranial fibrous xanthoma is presented, initially misdiagnosed as a chronic subdural hematoma.
- Computed tomography (CT) and magnetic resonance (MR) imaging revealed distinct characteristics of the subdural and clival masses.
- The patient experienced initial recovery with conservative management but later succumbed to cerebral infarction.
Findings:
- Histopathological examination confirmed the diagnosis of fibrous xanthoma.
- Postcontrast CT demonstrated intense homogeneous enhancement, while MR imaging showed iso- to low-intensity on T1-weighted and low-intensity on T2-weighted images.
- Autopsy confirmed the presence of fibrous xanthomas in multiple intracranial locations.
Implications:
- This report is the first to describe the use of MR imaging in diagnosing intracranial fibrous xanthoma.
- The unique imaging features identified may assist in differentiating this rare tumor from common intracranial parenchymal tumors.
- Further research into the characteristic imaging findings of intracranial fibrous xanthoma is warranted to improve diagnostic accuracy.