Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Meiotic spindle: sculpted by severing.

Katharina Ribbeck1, Timothy J Mitchison

  • 1Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, USA. Katharina_Ribbeck@hms.harvard.edu

Current Biology : CB
|November 7, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Methods for studying mucin-microbe interactions.

Methods in enzymology·2026
Same author

Mucin-induced metabolic reprogramming in <i>Pseudomonas aeruginosa</i> clinical isolates.

mSystems·2026
Same author

Rebinding drives cellular retention of small-molecule drugs with abundant targets.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

It's not just snot! : Mucus: Nature's Multifaceted Secretion.

EMBO reports·2026
Same author

Structure-based discovery of selective vaccinia-related kinase 1 inhibitors and fluorogenic active-site probes.

The Journal of biological chemistry·2026
Same author

Spatial control of Keratin 8 phosphorylation by Aurora B facilitates cytokinesis in cancer cells of epithelial origin.

The FEBS journal·2026
Same journal

A global response contributes to tissue size robustness upon local induction of apoptosis.

Current biology : CB·2026
Same journal

Prebilaterian origin of monoaminergic signaling.

Current biology : CB·2026
Same journal

CLASP-dependent microtubule stabilization generates microtubule-based protrusive forces during Drosophila epithelial morphogenesis.

Current biology : CB·2026
Same journal

Pigeons make slow, divergent eye movements during flight and large, convergent eye movements when landing.

Current biology : CB·2026
Same journal

Temperature signals drive grass secondary cell wall thickening.

Current biology : CB·2026
Same journal

Neuronal RNAi and oxygen-sensing circuit shape germline resilience to heat stress.

Current biology : CB·2026
See all related articles

Katanin, an AAA ATPase, is shown to stimulate microtubule production in the meiotic spindles of Caenorhabditis elegans oocytes. This finding clarifies the biological function of katanin in animal cells.

Area of Science:

  • Cell Biology
  • Molecular Biology
  • Genetics

Background:

  • Katanin is a conserved AAA ATPase known for severing microtubules.
  • Its precise biological role in animal cells remained largely unknown.

Purpose of the Study:

  • To elucidate the biological function of katanin in animal cells.
  • To investigate katanin's role in meiotic spindle formation.

Main Methods:

  • Utilized electron tomography.
  • Studied oocytes of the model organism Caenorhabditis elegans.

Main Results:

  • Katanin was found to stimulate microtubule production.
  • This stimulation occurs specifically within the meiotic spindles.

Related Experiment Videos

Conclusions:

  • Katanin plays a crucial role in microtubule dynamics during meiosis.
  • The study clarifies katanin's function in the context of meiotic spindle assembly in animal cells.