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Updated: Jul 19, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
Published on: June 10, 2025
Dubin-Johnson syndrome with systemic lupus erythematosus: a case report
Mamun-Al Mahtab1, Md Fazal Karim, Salimur Rahman
1Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. shwapnil@agni.com
Background:
Dubin-Johnson syndrome (DJS) is a rare clinical entity. We describe a case of DJS complicated by systemic lupus erythematosus (SLE).
Methods:
A case of congenital hyperbilirubinemia with SLE was evaluated systematically including review of history, physical examination for the stigmata of chronic liver disease, and other investigations.
Result:
Liver biopsy revealed a black liver with preserved architecture suggestive of DJS.
Conclusions:
SLE may develop in DJS. The relationship between DJS and SLE in this case is most likely a chance occurrence.
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