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Systemic candidiasis in a dog, developing spondylitis
Mitsuru Kuwamura1, Mika Ide, Jyoji Yamate
1Laboratory of Veterinary Pathology, Osaka Prefecture University, Osaka, Japan.
The Journal of Veterinary Medical Science
|November 7, 2006
Summary
A Shiba dog developed systemic candidiasis, a fungal infection caused by Candida albicans, leading to spinal inflammation (spondylitis) and widespread organ lesions. This rare condition ultimately proved fatal despite veterinary care.
Area of Science:
- Veterinary Pathology
- Mycology
- Canine Infectious Diseases
Background:
- Systemic fungal infections are uncommon in dogs.
- Candida albicans is a yeast typically found as normal flora, but can cause opportunistic infections.
Observation:
- A 4-year-old Shiba dog presented with pain and hypersensitivity, progressing to ataxia and hind-limb weakness.
- Postmortem examination revealed a thoracic vertebral mass and disseminated granulomatous lesions in multiple organs.
Findings:
- Histopathology confirmed granulomatous inflammation with fungal organisms identified as Candida albicans.
- Immunohistochemistry confirmed the presence of Candida albicans in the lesions.
- The case was diagnosed as systemic candidiasis with spondylitis.
Implications:
- This case highlights the potential for Candida albicans to cause severe systemic disease and spondylitis in dogs.
- Early recognition and diagnosis of systemic candidiasis are crucial for potential treatment strategies.
- Further research into risk factors and treatment protocols for canine systemic candidiasis is warranted.
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