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Related Experiment Videos

Bite the hand that sprays you.

Sameer B Ismailjee1, Jack M Bernstein, Steven D Burdette

  • 1Department of Medicine, Boonshoft School of Medicine, Wright State University, and the Department of Veterans Affairs Medical Center, Dayton, OH 45428, USA.

Skinmed
|November 7, 2006
PubMed
Summary
This summary is machine-generated.

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A traveler to Costa Rica developed a sporotrichoid pattern of skin lesions, diagnosed as cutaneous leishmaniasis caused by Leishmania panamensis. Oral miltefosine effectively treated the infection.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Tropical Medicine

Background:

  • Cutaneous leishmaniasis is a parasitic disease transmitted by sandflies, prevalent in tropical and subtropical regions.
  • Leishmania panamensis is a species of Leishmania parasite known to cause cutaneous leishmaniasis, particularly in Central and South America.
  • Exposure to infected sandflies during travel to endemic areas is the primary risk factor for acquiring the infection.

Observation:

  • A 56-year-old man presented with a hand lesion after returning from Costa Rica.
  • The patient developed multiple ulcerated nodules in a sporotrichoid pattern on his right arm.
  • Lesions included an ulcer on the dorsum of the right hand, an ulcerated nodule near the right earlobe, and an ulcer on the right wrist.

Findings:

Related Experiment Videos

  • Skin biopsy confirmed cutaneous leishmaniasis due to Leishmania panamensis.
  • The clinical presentation included multiple nodular lesions progressing in a linear, sporotrichoid fashion along the lymphatic drainage of the right arm.
  • No mucocutaneous involvement was observed.

    • Implications:

    • This case highlights the importance of considering cutaneous leishmaniasis in travelers presenting with unusual skin lesions after visiting endemic areas.
    • Early diagnosis through skin biopsy and appropriate treatment are crucial for managing cutaneous leishmaniasis.
    • Miltefosine demonstrated efficacy as an oral treatment option for Leishmania panamensis-induced cutaneous leishmaniasis.