Botulinum toxin and pregnancy
Related Experiment Video
Updated: Jul 19, 2026

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays
Published on: March 3, 2014
1Dermatology Cosmetic Center Federal University of São Paulo, Brazil. erica@dermatologia.com.br
Abstract:
The overall use of botulinum toxin type A in cosmetic procedures continues to rise, and the incidental exposures of pregnant women to the drug can occur. The author describes 2 patients who received botulinum toxin type A injections during pregnancy. The first patient was a 34-year-old woman who received 54 units of botulinum toxin type A to treat periorbital lines (crow's feet) unaware that she was 6 weeks pregnant. She had a healthy term baby delivered by cesarean section; Apgar scores were 9/10. The second patient was a 37-year-old woman who received 65 units of botulinum toxin type A to treat facial dynamic lines (forehead, glabelar, and periorbital), unaware that she was 5 weeks pregnant. She had a healthy term baby delivered by cesarean section; Apgar scores were 9/10. The 2 patients were injected only once in the first trimester. Both cases did not have any complications or detectable adverse effects on the fetuses.
More Related Videos
Related Concept Videos
Botulism
Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin
The binding of dantrolene to the RYR1...
Tetanus
Skeletal Muscle Relaxants: Therapeutic Uses
Teratogenicity
Nondepolarizing (Competitive) Neuromuscular Blockers: Pharmacological Actions
Although all competitive neuromuscular blockers are designed...

