Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Devic disease].

Caroline Papeix1

  • 1Service de neurologie 1, Hôpital de la Salpêtrière, Paris (75).

Presse Medicale (Paris, France : 1983)
|November 7, 2006
PubMed
Summary
This summary is machine-generated.

Neuromyelitis optica (Devic disease) is a rare autoimmune disorder causing optic neuritis and myelitis. Identifying specific antibodies (IgG NMO) aids in understanding and managing this severe condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A predictive tool for early treatment escalation after initiation of moderate-efficacy therapy in pediatric-onset multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)·2026
Same author

French NOMADMUS Cohort Overview: Landscape Evolution of AQP4+NMOSD and MOGAD From 2010 to 2024.

Neurology·2026
Same author

Comparative effectiveness of ocrelizumab in subgroups of patients with multiple sclerosis: a multi-registry observational cohort study.

Journal of neurology, neurosurgery, and psychiatry·2026
Same author

External validation and improvement of an algorithm that identifies multiple sclerosis relapses in the French national healthcare claims database.

Multiple sclerosis and related disorders·2026
Same author

[Criteria for choosing treatment of multiple sclerosis].

La Revue du praticien·2026
Same author

Differences in Use of Disease-Modifying Therapies Between Patients With Late-Onset and Adult-Onset Relapsing-Remitting Multiple Sclerosis.

Neurology·2026

Area of Science:

  • Neuroimmunology
  • Neurology
  • Autoimmune Diseases

Background:

  • Devic disease, or neuromyelitis optica (NMO), is a severe neurological disorder.
  • Characterized by optic neuritis and myelitis, it involves demyelination and axon loss.
  • Specific NMO-specific antibodies (IgG NMO) have been recently identified.

Purpose of the Study:

  • To summarize the key pathological and clinical features of Devic disease.
  • To highlight the significance of newly identified NMO-specific antibodies.
  • To discuss current therapeutic strategies for relapse prevention.

Main Methods:

  • Review of clinical and pathological findings in Devic disease.
  • Analysis of recent discoveries in NMO antibody identification.

Related Experiment Videos

  • Evaluation of immunosuppressive treatment efficacy.

    • Main Results:

    • Devic disease involves demyelination, axon loss, and specific immunoglobulin deposits (IgM).
    • The identification of IgG NMO antibodies is a significant diagnostic advancement.
    • Immunosuppressive therapy is the current standard for preventing relapses.

    Conclusions:

    • Neuromyelitis optica is a distinct severe neurological condition.
    • IgG NMO antibodies are crucial biomarkers for Devic disease.
    • Effective management focuses on immunosuppression to prevent disease recurrence.