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Published on: September 19, 2016
[BCG Today]
1Institut de veille sanitaire, Département des maladies infectieuses, Saint-Maurice (94).
Insights
France shifted its BCG vaccination policy, discontinuing routine revaccinations and post-vaccination tests. A selective approach for high-risk children is now favored, alongside enhanced tuberculosis control measures.
Area of Science:
- Public Health
- Infectious Disease Epidemiology
- Vaccination Policy
Background:
- French BCG vaccination policy historically mandated pre-entry vaccination and revaccination for tuberculin-negative children.
- Policy reassessment in 2004 led to the discontinuation of routine revaccinations and post-vaccination tuberculin tests.
- The multipuncture BCG vaccine, used for over 90% of primary vaccinations, was withdrawn in 2006, complicating vaccination strategies.
Purpose of the Study:
- To evaluate the epidemiological effects of selective BCG vaccination versus complete discontinuation.
- To analyze the risks and benefits associated with different BCG vaccination strategies.
- To inform public health policy regarding childhood tuberculosis prevention in France.
Main Methods:
- Epidemiological assessment of vaccination strategies.
- Risk-benefit analysis of selective versus universal BCG vaccination.
- Review of public health recommendations and policy changes.
Main Results:
- The High Council of Public Hygiene approved the principle of selective BCG vaccination for children.
- Reinforcement of other tuberculosis control measures was advised as a prerequisite for selective vaccination.
- The discontinuation of routine revaccinations and post-vaccination tests was implemented in 2004.
Conclusions:
- France has transitioned from universal BCG vaccination to a selective strategy for high-risk children.
- Enhanced non-vaccine-related tuberculosis control measures are crucial for protecting children.
- The policy shift reflects an updated risk-benefit assessment in light of epidemiological data and vaccine availability.
Abstract:
Until recently, French BCG vaccination policy required BCG vaccination before entry into day-care centers or school and the revaccination of tuberculin-negative children. Recent reassessment of this policy led in 2004 to the discontinuation of all revaccinations and of postvaccination tuberculin tests except those performed as part of tuberculosis diagnosis or in the monitoring of healthcare and social workers, for whom BCG vaccination remains mandatory. After an epidemiologic assessment of the effect of either selective vaccination of high-risk children or discontinuation of all BCG vaccination and analysis of balance of risks and benefits of each option, the High Council of Public Hygiene (Infectious diseases section) approved the principle of selective vaccination of children. As a prerequisite to this implementation of this strategy, however, the council advised the Ministry of Health that other control measures to decrease the risk of tuberculosis in children should be reinforced. This issue is made more complex by the withdrawal in 2006 of the multipuncture vaccine, used in France in more than 90% of primary BCG vaccinations.
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