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[Effect of sideropenia in mothers on hematologic indicators and iron stores in newborn infants]
Insights
Maternal iron status directly impacts newborn iron stores. Prenatal iron therapy is crucial for preventing infant anemia and ensuring adequate iron for the first year.
Area of Science:
- Hematology
- Maternal-Fetal Medicine
- Nutritional Science
Context:
- Investigated iron status markers in 633 mothers and newborns.
- Assessed total hemoglobin, transport iron, serum ferritin, and transferrin saturation.
Purpose:
- To determine the correlation between maternal and neonatal iron status.
- To understand the influence of maternal iron deficiency on infant iron stores.
Summary:
- Found a direct correlation between maternal and neonatal iron status.
- Maternal iron deficiency duration and severity significantly impact newborn iron store formation.
- Inadequate antenatal iron stores due to maternal deficiency cause infant sideropenia and anemia.
Impact:
- Preventive iron therapy during pregnancy reduces maternal iron-deficient anemia.
- Ensures better neonatal iron status, meeting infant needs for the first year of life.
Abstract:
The concentrations of total hemoglobin, transport iron, serum ferritin, serum total iron binding, the transferrin saturation rate, unbound erythrocyte porphyrins have been examined in 633 mothers and their newborns. A direct correlation was found between the neonatal and maternal iron status. The formation of the iron store in newborns was significantly influenced by the duration and severity of maternal iron deficiency. Deficient iron storage in antenatal life due to maternal iron deficiency was a major cause of sideropenia and anemia in the infants. Preventive iron therapy during pregnancy prevented iron-deficient anemia in mothers and provided a better neonatal iron status to meet the requirements of the first year of life.