Related Experiment Video
Updated: Jul 19, 2026

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
Outcome of percutaneous coronary intervention in HIV-infected patients
Amit Segev1, Warren J Cantor, Bradley H Strauss
1The Roy and Ann Foss Interventional Cardiology Research Program, Terrence Donnelly Heart Center, St Michael's Hospital, Toronto, Ontario, Canada.
Insights
Percutaneous coronary interventions (PCI) in HIV-infected patients show poor long-term outcomes. Routine use of drug-eluting stents is recommended for this high-risk group.
Area of Science:
- Cardiology
- Infectious Diseases
- Interventional Cardiology
Background:
- Human Immunodeficiency Virus (HIV) infection is associated with increased cardiovascular risk.
- Understanding the outcomes of cardiovascular interventions in HIV-infected patients is crucial.
Purpose of the Study:
- To evaluate the long-term outcomes of percutaneous coronary interventions (PCI) in patients with HIV infection.
- To determine the efficacy and safety of PCI in this specific patient population.
Main Methods:
- Retrospective analysis of 12 HIV-infected patients who underwent PCI.
- Assessment of clinical and angiographic outcomes, including mortality, restenosis, and symptom recurrence.
Main Results:
- High rates of adverse events were observed, including two deaths from HIV-related infections.
- Seven patients experienced severe restenosis or angina, necessitating further interventions.
- Only three patients remained symptom-free at long-term follow-up.
Conclusions:
- HIV-infected patients represent a high-risk group for PCI.
- Routine use of drug-eluting stents is recommended to improve outcomes in these patients.
Abstract:
We report the long-term outcome of percutaneous coronary interventions (PCI) in 12 HIV-infected patients. Two patients died from a HIV-related infection and seven patients suffered from severe clinical and/or angiographic restenosis requiring additional interventions or causing severe angina pectoris. Only three patients remained symptom free. We conclude that HIV-infected patients should be considered as high risk group and treated routinely with drug-eluting stents.
Related Concept Videos
Sexually Transmitted Infections
Cryptococcal Meningitis
Retrovirus Life Cycles
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Acute Coronary Syndrome III: Diagnostic Studies
