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Updated: Jul 19, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
A multidisciplinary approach to reducing outbreaks and nosocomial MRSA in a university-affiliated hospital
Maryam Salaripour1, Pat McKernan, Roslyn Devlin
1Department of Risk Management & Quality Improvement, St. Michael's Hospital, Toronto, ON. salaripourm@smh.toronto.on.ca
Abstract:
Endemic MRSA (methicillin-resistant Staphylococcus aureus) colonization and infection has been shown to increase morbidity, length of stay and hospital cost. Prevention of transmission demands innovative approaches. Descriptive statistics were used to determine high-incidence units. On admission, patients with a history of previous admission to a healthcare institution within the past six months were screened for MRSA. Point prevalence studies were carried out on units with more than two nosocomial (hospital-acquired) MRSA patient isolates within a four-week period. A multidisciplinary team from Infection Control and clinical units determined potential contributing factors. Recommendations included increased organism-specific education for staff, environmental cleaning and elimination of sources of transmission. Control charts to monitor nosocomial incidence rates were provided to those units that historically had a high prevalence of MRSA infections and colonization. Compliance with the infection control isolation guidelines and screening guidelines was monitored by the service. There was a 60% decrease in nosocomial MRSA between 2000 and 2001. Unit feedback was extended throughout the hospital. This decrease has been sustained since 2001 with annual rates per 1000 patient-days of 0.61 for 2000, 0.21 for 2001, 0.24 for 2002, 0.25 for 2003, 0.35 for 2004 and 0.19 for 2005.
Insights
Implementing targeted infection control strategies significantly reduced methicillin-resistant Staphylococcus aureus (MRSA) hospital-acquired infections by 60%. Sustained vigilance in screening and environmental cleaning maintains these vital improvements in patient safety.
Area of Science:
- Healthcare Epidemiology
- Infectious Disease Control
- Public Health
Background:
- Endemic methicillin-resistant Staphylococcus aureus (MRSA) significantly increases patient morbidity, hospital stays, and healthcare costs.
- Effective prevention of MRSA transmission requires innovative and targeted strategies within healthcare settings.
Purpose of the Study:
- To evaluate the impact of a multidisciplinary infection control program on reducing nosocomial MRSA incidence.
- To identify high-incidence units and implement specific interventions to control MRSA spread.
Main Methods:
- Descriptive statistics identified high-incidence units for MRSA.
- Screening of at-risk patients upon admission and point prevalence studies were conducted.
- Interventions included staff education, enhanced environmental cleaning, and monitoring of control charts.
Main Results:
- A 60% decrease in nosocomial MRSA was observed between 2000 and 2001.
- MRSA incidence rates per 1000 patient-days decreased from 0.61 in 2000 to 0.21 in 2001.
- The reduced incidence was sustained from 2001 through 2005, with rates ranging from 0.19 to 0.35.
Conclusions:
- A comprehensive, multidisciplinary approach to infection control is effective in reducing MRSA.
- Sustained implementation of screening, education, and environmental hygiene is crucial for long-term MRSA control.
- The program demonstrated significant success in lowering hospital-acquired MRSA rates.
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