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Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
Published on: November 29, 2024
[Coronary heart disease in patients with diabetes mellitus]
Masafumi Nakayama1, Hisao Ogawa
1Department of Cardiovascular Medicine, Graduate School of Sciences, Kumamoto University.
Insights
Diabetes mellitus significantly increases the risk of coronary artery disease, leading to a higher likelihood of severe heart conditions and cardiovascular events in affected patients.
Area of Science:
- Cardiology
- Endocrinology
- Public Health
Context:
- Diabetes mellitus is a significant risk factor for coronary artery disease (CAD).
- Diabetic patients face a 2-4 times higher risk of cardiovascular disease (CVD) mortality and morbidity.
- Many diabetic patients with CAD present with severe multi-vessel or stenosed coronary arteries.
Purpose:
- To review the assessment of coronary heart disease risk through glucose level measurement.
- To discuss the prognosis of patients with diabetes mellitus.
- To explore strategies for preventing cardiovascular events in diabetic individuals.
Summary:
- This review focuses on the heightened risk of severe coronary artery disease in diabetic patients.
- It examines methods for evaluating cardiovascular risk using glucose levels.
- The article also covers the long-term outlook and preventative measures for cardiovascular events in this population.
- The increasing prevalence of diabetes in Japan necessitates a focus on these aspects.
Impact:
- Provides clinicians with updated information on managing cardiovascular risk in diabetic patients.
- Highlights the importance of glucose monitoring for predicting cardiovascular events.
- Aims to improve patient outcomes by informing prevention strategies for cardiovascular disease in diabetes mellitus.
Abstract:
Diabetes mellitus is a well-recognized risk-factor for coronary artery disease. It is known that diabetic patients have a two-to fourfold increased risk of mortality or morbidity for cardiovascular diseases compared with the general population. Further, many diabetic patients with coronary heart disease have severe diseased coronary arteries: multi-vessel disease and/or severe stenosed vessel(s). In Japan, the prevalence of diabetic patients is rapidly increasing in these days. This article will review the evaluation for risk of coronary heart disease by measuring glucose level, the prognosis of diabetic patients, and the prevention of cardiovascular event in the patients with diabetes mellitus.
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