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Related Experiment Videos

Antidepressants and sexual dysfunction.

U Werneke1, S Northey, D Bhugra

  • 1Department of Psychiatry, Homerton University Hospital, London, UK. uwerneke@easynet.co.uk [corrected]

Acta Psychiatrica Scandinavica
|November 8, 2006
PubMed
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Antidepressant use can cause sexual dysfunction in up to 70% of depression patients. This review explores prevalence and treatments for antidepressant-induced sexual dysfunction, highlighting its impact on depression management.

Area of Science:

  • Psychiatry
  • Pharmacology
  • Sexual Medicine

Background:

  • Sexual dysfunction is a common issue for patients with depression.
  • Sexual dysfunction is a recognized side-effect of antidepressant medications.

Purpose of the Study:

  • To review the prevalence of psychosexual dysfunction linked to antidepressants.
  • To examine specific treatment options for antidepressant-induced sexual dysfunction.

Main Methods:

  • A comprehensive literature review was conducted.
  • Searches included Medline and Cochrane databases.

Main Results:

  • Up to 70% of patients with depression may experience sexual dysfunction.
  • Tricyclic antidepressants, SSRIs, and venlafaxine are most associated with sexual dysfunction.

Related Experiment Videos

  • Non-serotonergic antidepressants and duloxetine are least likely to cause sexual dysfunction.
  • Treatment options include alternative antidepressants or 'antidotes'.

    • Conclusions:

    • Sexual dysfunction associated with antidepressants is potentially preventable and treatable.
    • Routine screening for sexual function is crucial for early identification.
    • Ignoring sexual dysfunction can worsen depression and hinder treatment adherence.