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The persistence of depression score.

J Spijker1, R de Graaf, J Ormel

  • 1Netherlands Institute of Mental Health and Addiction, Utrecht, The Netherlands. jspijker@trimbos.nl

Acta Psychiatrica Scandinavica
|November 8, 2006
PubMed
Summary

Researchers developed the Persistence of Depression Score (PDS) to predict major depressive episode (MDE) duration. This score helps identify individuals at higher risk for prolonged MDE, aiding clinical treatment decisions.

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Area of Science:

  • Psychiatry
  • Epidemiology
  • Clinical Psychology

Background:

  • Major depressive episode (MDE) can be persistent, impacting individuals and healthcare systems.
  • Predicting MDE persistence is crucial for effective treatment planning and resource allocation.

Purpose of the Study:

  • To develop a predictive score for major depressive episode (MDE) persistence.
  • To utilize previously identified determinants of MDE persistence in score construction.

Main Methods:

  • Data from 250 general population subjects with new MDE (DSM-III-R) from the Netherlands Mental Health Survey and Incidence Study (NEMESIS).
  • Composite International Diagnostic Interview used for data collection.
  • Proportional hazards models and bootstrapping techniques applied to create a risk score.

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Main Results:

  • The 12-month risk of MDE persistence was 23%.
  • The developed score incorporated physical illness, social support, depression severity, recurrence, and prior episode duration.
  • Predicted risks ranged from 7% to 40% across score categories.

Conclusions:

  • The Persistence of Depression Score (PDS) was constructed and demonstrated reasonable predictive performance.
  • The PDS has potential clinical utility in guiding treatment decisions for MDE.