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Updated: Jul 19, 2026
09:09
In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
An experimentally derived stress resultant shell model for heart valve dynamic simulations
Hyunggun Kim1, Krishnan B Chandran, Michael S Sacks
1Department of Biomedical Engineering, University of Iowa, Iowa City, IA 52242, USA.
Annals of Biomedical Engineering
|November 8, 2006
Summary
A new finite shell element model enhances computational simulations of heart valve dynamics. This advanced model provides more accurate insights into native and bioprosthetic valve function under various conditions.
Area of Science:
- Computational mechanics
- Biomedical engineering
- Cardiovascular research
Background:
- Accurate simulation of heart valve dynamics is crucial for understanding cardiovascular health.
- Existing models often lack the fidelity to capture complex native and bioprosthetic valve behaviors.
Purpose of the Study:
- To develop a novel finite shell element model for realistic heart valve simulations.
- To improve the accuracy of computational models for native and bioprosthetic heart valves.
Main Methods:
- Developed a fully nonlinear stress resultant shell element.
- Implemented experimentally derived in-plane and bending behaviors.
- Validated the model using planar biaxial extension and three-point bending tests.
Main Results:
- The model demonstrated excellent fidelity in validation studies.
- Simulations revealed significant differences in deformation compared to isotropic models.
- The developed model accurately captures heart valve mechanics.
Conclusions:
- The new finite shell element model offers a more realistic simulation of heart valve dynamics.
- This tool can be used to study heart valve function in physiological and pathological states.
- The model's flexibility allows incorporation of various constitutive models for diverse applications.
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