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Updated: Jul 19, 2026

Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development

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Alcohol use before and during pregnancy: a population-based study.

Astrid Alvik¹, Sonja Heyerdahl, Tor Haldorsen

¹Sogn Centre for Child and Adolescent Psychiatry, Ulleval University Hospital, University of Oslo, Oslo, Norway. astrid.alvik@medisin.uio.no

Acta Obstetricia Et Gynecologica Scandinavica

|November 9, 2006

Summary

Many women drink alcohol before pregnancy recognition, with nearly 60% engaging in binge drinking. This pattern, established before fetal development is known, may negatively impact fetal health.

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Area of Science:

Reproductive Health
Maternal Health
Public Health

Background:

Limited population-based data exists on alcohol consumption and binge drinking patterns before and during pregnancy.
Understanding these patterns is crucial for identifying potential risks to fetal development.

Purpose of the Study:

To estimate alcohol consumption and binge drinking prevalence before and during early pregnancy.
To identify factors associated with alcohol use and binge drinking during pregnancy.

Main Methods:

A longitudinal questionnaire study was conducted with a representative sample of pregnant women in Oslo, Norway.
Data collected included T-ACE screening, alcohol frequency, Standard Units (SU) per occasion, SU/week, and binge drinking (>or=5 SU per occasion).
Statistical analyses included binary logistic regression, Student's t-test, and Pearson's chi square.

Main Results:

89% reported alcohol use pre-pregnancy, decreasing to 23% after week 12. Binge drinking was reported by 59% pre-pregnancy and 25% in early pregnancy (weeks 0-6).
85% altered drinking patterns upon pregnancy recognition, even if the pregnancy was planned for fetal welfare.
Alcohol use during pregnancy was associated with older age, smoking, higher pre-pregnancy SU/week, anxiety, higher income, and partner's education; however, only smoking and T-ACE positivity predicted binge drinking.

Conclusions:

A significant proportion of women exhibit pre-pregnancy alcohol consumption patterns that may pose risks to fetal development.
Early pregnancy drinking and binge drinking are prevalent, highlighting the need for targeted interventions.
Factors like smoking and risk screening (T-ACE) are key predictors of high-risk drinking behaviors during pregnancy.