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Adrenocortical oncocytoma in a child
Fabienne Gumy-Pause1, Massimo Bongiovanni, Barbara Wildhaber
1Department of Pediatrics, Hematology/Oncology Unit, University Hospital of Geneva, Switzerland. fabienne.gumypause@medecine.unige.ch
Pediatric Blood & Cancer
|November 9, 2006
Summary
Adrenocortical oncocytoma, a rare adult tumor, was diagnosed in a 12-year-old girl with an adrenal mass. This pediatric case highlights the importance of considering rare diagnoses in young patients with adrenal tumors.
Area of Science:
- Endocrinology
- Pediatric Oncology
- Pathology
Background:
- Adrenocortical oncocytoma is an exceptionally rare epithelial tumor typically diagnosed in adults.
- Pediatric adrenal masses often present with hormonal imbalances or mass effect symptoms.
Observation:
- A 12-year-old female presented with a left adrenal mass accompanied by abdominal pain, fatigue, and acne vulgaris.
- Laboratory tests revealed elevated androstenedione and total testosterone levels.
Findings:
- Histological, immunohistochemical, and ultrastructural analyses confirmed the diagnosis of adrenocortical oncocytoma.
- This represents a rare pediatric case of adrenocortical oncocytoma.
Implications:
- This case expands the known age spectrum for adrenocortical oncocytoma.
- It underscores the necessity of comprehensive diagnostic evaluation for pediatric adrenal masses, even those with rare histologies.
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