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Phase II study of pibenzimol in pancreatic cancer. A Southwest Oncology Group study

E H Kraut¹, T Fleming, M Segal

¹Ohio State University Health Center, Columbus.

Investigational New Drugs

|February 1, 1991

Abstract:

Twenty-three patients with advanced pancreatic adenocarcinoma were treated with Pibenzimol utilizing a daily intravenous schedule for five days. There were no objective responses seen. The major toxicity was pancreatic with grade 3 hyperglycemia in eleven patients. Pibenzimol is inactive in patients with advanced pancreatic adenocarcinoma.

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