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Updated: Jul 19, 2026

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
Published on: September 25, 2016
Subtle computed tomography abnormalities in cerebral deep sinus thrombosis.
Tomomi Iwashita1, Kazuo Kitazawa, Jun-Ichi Koyama
1Department of Emergency and Intensive Care Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Early diagnosis of cerebral deep sinus thrombosis is crucial. Missed subtle findings on initial CT scans can lead to delayed treatment and poor outcomes in patients presenting with headache and vomiting.
Area of Science:
- Neurology
- Radiology
Background:
- Cerebral deep sinus thrombosis is a rare but serious condition.
- Prompt diagnosis and treatment are essential for patient outcomes.
Observation:
- A 46-year-old woman presented with headache and vomiting, with initial neurological examination and CT scan showing no abnormalities.
- Deterioration in consciousness led to further imaging, revealing an ischemic lesion and deep sinus occlusion.
Findings:
- Magnetic resonance imaging and cerebral angiography confirmed straight sinus occlusion.
- Despite anticoagulant therapy, the patient developed a hematoma and brain swelling, ultimately succumbing to the condition.
- Review of the initial CT scan identified subtle, early signs of deep venous thrombosis that were initially overlooked.
Implications:
- This case highlights the importance of recognizing subtle early signs of cerebral deep sinus thrombosis.
- Enhanced vigilance and advanced imaging may be necessary in patients with persistent or worsening symptoms.
- Timely diagnosis and intervention are critical for improving survival rates in cerebral deep sinus thrombosis.
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