Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Neural Regulation

Neural Regulation

Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Iron deficiency and iron deficiency anemia].

[Rinsho ketsueki] The Japanese journal of clinical hematology·2026

Same author

Ralstonia pseudosolanacearum PhcQ Controls Quorum Sensing-Dependent Phenotypes by Binding PhcA and Maintaining Its Protein Stability.

Molecular plant pathology·2026

Same author

The Natural Quassinoid Brusatol Enhances Venetoclax Efficacy and Overcomes Resistance in Myeloid Leukemias.

Cancer science·2026

Same author

Iron recovery dynamics after whole blood donation and the effect of low-dose iron supplementation in Japanese donors.

Vox sanguinis·2026

Same author

Complete genome sequences of <i>Vibrio</i> species, degraders of sulfated polysaccharide ulvan extracted from a green algae <i>Ulva ohnoi</i>.

Microbiology resource announcements·2026

Same author

Cost-effectiveness of blinatumomab as post-remission therapy in adults with measurable residual disease-negative, Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia.

British journal of haematology·2026

Search research articles

Related Experiment Video

Updated: Jul 18, 2026

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube (SWCNT)-delivered MALAT1 Antisense Oligos

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube (SWCNT)-delivered MALAT1 Antisense Oligos

Published on: December 13, 2018

[A neuron specific enolase-producing multiple myeloma].

Junko Jimbo¹, Kazuya Sato, Katsuya Ikuta

¹Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical College.

[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology

|November 11, 2006

Summary

This study reports a rare case of IgG-lambda multiple myeloma presenting as a chest-wall plasmacytoma. The myeloma cells produced neuron-specific enolase (NSE), which normalized after treatment.

More Related Videos

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

Related Experiment Videos

Last Updated: Jul 18, 2026

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube (SWCNT)-delivered MALAT1 Antisense Oligos

Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube (SWCNT)-delivered MALAT1 Antisense Oligos

Published on: December 13, 2018

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice

Published on: January 7, 2019

Area of Science:

Oncology
Hematology
Biochemistry

Background:

Multiple myeloma is a plasma cell malignancy.
Extramedullary plasmacytomas can occur in various locations.
Neuron-specific enolase (NSE) is a biomarker typically associated with neuroendocrine tumors.

Observation:

A 53-year-old woman presented with chest-wall pain, a chest-wall mass, pleural effusion, anemia, hypercalcemia, and elevated IgG levels.
Diagnostic workup revealed IgG-lambda monoclonal protein and elevated NSE.
Biopsy confirmed atypical plasma cell proliferation consistent with multiple myeloma and chest-wall plasmacytoma.

Findings:

Atypical plasma cells stained positive for cytoplasmic CD38 and IgG-lambda.
Immunostaining demonstrated diffuse NSE expression within the myeloma cells, suggesting NSE production by these malignant cells.
Treatment with chemotherapy and radiotherapy led to tumor regression and normalization of IgG and NSE levels.

Implications:

This case adds to the limited literature on NSE-producing multiple myeloma.
Elevated NSE may serve as a potential biomarker for myeloma activity in specific cases.
The findings highlight the diverse clinical presentations of multiple myeloma and the potential for unusual biomarker expression.