Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Choroid plexus involvement in malignant lymphoma. Case report].

K Fukui1, K Okamura, M Watanabe

  • 1Department of Neurosurgery, Toyohashi Municipal Hospital, Aichi.

Neurologia Medico-Chirurgica
|January 1, 1990
PubMed
Summary

Malignant lymphoma rarely affects the choroid plexus, presenting as mass lesions. This case highlights diffuse large B-cell lymphoma infiltrating the choroid plexus, leading to systemic disease and patient expiration.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of duloxetine on pain and walking distance in neuropathic pain models via modulation of the spinal monoamine system.

European journal of pain (London, England)·2017
Same author

Community-based screening intervention for depression affects suicide rates among middle-aged Japanese adults - ERRATUM.

Psychological medicine·2017
Same author

Community-based screening intervention for depression affects suicide rates among middle-aged Japanese adults.

Psychological medicine·2017
Same author

Isolation and Identification of a Pyrogallol Oxidase Producing Microorganism and the Enzyme Production.

Bioscience, biotechnology, and biochemistry·2016
Same author

Purification and Characterization of Arctium lappa L. (Edible Burdock) Polyphenol Oxidase.

Bioscience, biotechnology, and biochemistry·2016
Same author

A Novel Laccase Inhibitor, N-Hydroxyglycine, Produced by Penicillium citrinum YH-31.

Bioscience, biotechnology, and biochemistry·2016

Area of Science:

  • Neurology
  • Oncology
  • Pathology

Background:

  • Malignant lymphoma involvement of the choroid plexus is an uncommon presentation.
  • Non-Hodgkin's lymphoma, particularly diffuse large B-cell type, can manifest with central nervous system lesions.

Observation:

  • A 53-year-old female presented with neurological symptoms including headache, diplopia, and gait disturbance, alongside swollen lymph nodes.
  • Imaging revealed enhanced masses in the lateral and fourth ventricles, confirmed as diffuse large B-cell type non-Hodgkin's lymphoma via biopsy.
  • Surgical exploration identified a vascular tumor at the choroid plexus, infiltrating adjacent brain tissue, subependymal, perivascular spaces, and Virchow-Robin spaces.

Findings:

  • Pathological examination confirmed diffuse large B-cell lymphoma infiltrating the choroid plexus and adjacent brain structures.

Related Experiment Videos

  • The tumor was highly vascular and located at the choroid plexus of the right lateral ventricle.
  • Lymphoma cells extensively infiltrated the subependymal and perivascular spaces of the choroid plexus and surrounding brain tissue.

    • Implications:

    • This case highlights the importance of considering lymphoma in the differential diagnosis of intraventricular masses, even in early systemic stages.
    • Aggressive treatment including surgery, whole brain irradiation, and chemotherapy may not prevent systemic progression and mortality in advanced cases.
    • Further research into the mechanisms of choroid plexus infiltration by lymphoma is warranted.