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Updated: Jul 18, 2026

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
Published on: April 11, 2019
Management of a young patient with combined autoimmunity: Evans syndrome: a case report
Andres Pinto1, Rochelle G Lindemeyer, Faizan Alawi
1Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA. apinto@pobox.upenn.edu
Abstract:
Management of patients with autoimmune disease can present a challenge for clinicians. Combinations of autoimmune disorders carry a worse prognosis and are often difficult to diagnose. Evans syndrome is a rare hematologic disorder characterized by the concurrent presentation of autoimmune hemolytic anemia and immune thrombocytopenic purpura. This paper reports the first case of the dental management of a young patient with Evans, discusses the current literature surrounding the differential diagnosis and treatment of Evans syndrome, and suggests a guide for the oral medicine, pediatric dentist, or hospital dental clinician when treating these patients.
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