Related Experiment Video
Updated: Jul 18, 2026
Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
Published on: January 29, 2019
Radioimmunotherapy for non-Hodgkin's lymphoma
Pat Liebenguth1, Susan Vogt Temple
1Department of Radiation Oncology, Baptist Hospital, Pensacola, FL 32501, USA. pat.liebenguth@bhcpns.org
Objectives:
To describe the rationale for radioimmunotherapy as a treatment of non-Hodgkin's lymphoma. To present the similarities and differences in the two radioimmunotherapies and the nursing implications in caring for patients receiving these agents.
Data Sources:
Published literature and review of published clinical trials.
Conclusion:
Radiolabeled monoclonal antibodies bind to specific antigens and provide a means of targeting tumor cells with cytotoxic radioactivity. The infusion of radiolabeled monoclonal antibodies requires an understanding of antibody therapy, radiation therapy, and principles of time, distance, and shielding.
Implications For Nursing Practice:
As the use of radioimmunotherapy grows, nurses must be aware of the background for, logistics of, and follow-up required for patients receiving this form of radiation treatment.
