Related Experiment Video
Updated: Jul 18, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Use of molecular adsorbent recirculating system in acute liver failure attributable to dengue hemorrhagic fever
Alvin Penafiel1, Anantham Devanand, Han Khim Tan
1Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore. agp1502@aim.com
Abstract:
Fulminant liver failure is an uncommon but life-threatening complication of severe dengue infection. Molecular adsorbent recirculating system (MARS), which reverses hepatic encephalopathy, is an emerging important element in the armamentarium of organ support in the intensive care unit in patients suffering from acute liver failure. We report an intensive care unit case of fulminant liver failure secondary to dengue hemorrhagic fever, which was supported with MARS. MARS led to rapid reversal of biochemical profile and encephalopathy, resulting in early extubation and intensive care unit discharge.
Related Concept Videos
Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
Effect of Hepatic Disease on Pharmacokinetics: Drug Dosing and Hepatic Blood Flow
Acute Kidney Injury I: Introduction
