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Updated: Jul 18, 2026

A Next-generation Tissue Microarray (ngTMA) Protocol for Biomarker Studies
Published on: September 23, 2014
International Agency for Research on Cancer workshop on 'Expression array analyses in breast cancer taxonomy'
Sean V Tavtigian1, Marco A Pierotti, Anne-Lise Børresen-Dale
1Genetic Susceptibility Group, Genetics and Epidemiology Cluster, International Agency for Research on Cancer World Health Organization 150 Cours Albert-Thomas, 69372 Lyon Cedex 08, France.
Abstract:
In May 2006, a workshop on Expression array analyses in breast cancer taxonomy was held at the International Agency for Research on Cancer (IARC). The workshop covered an array of topics from the validity of the currently defined breast tumor subtypes and other expression profile-based signatures to the technical limitations of expression analysis and the types of platforms on which these omics results will eventually reach clinical practice. Overall, the workshop participants believed firmly that tumor taxonomy is likely to yield improved prognostic and predictive markers. Even so, further standardization and validation are required before clinical trials are set in motion.
