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Published on: September 12, 2014
Amygdala reactivity to emotional faces at high and low intensity in generalized social phobia: a 4-Tesla functional
K Lira Yoon1, Daniel A Fitzgerald, Mike Angstadt
1Brain Imaging and Emotions Laboratory, Department of Psychiatry, University of Chicago, Chicago, IL 60637-1470, USA.
Abstract:
Using functional magnetic resonance imaging, we measured amygdala reactivity to faces varying on emotional intensity in subjects with generalized social phobia (GSP) and matched healthy controls, and observed greater bilateral activation to high (vs. low) intensity expressions in the phobic group, suggesting that more arousing social-emotional cues contribute to limbic hyperactivity in GSP.
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