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Updated: Jul 18, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Hibernoma: MRI features in eight consecutive cases.

J C Lee¹, A Gupta, A Saifuddin

¹Department of Radiology, The London Bone and Soft Tissue Tumour Service, London, UK.

Clinical Radiology

|November 14, 2006

Summary

Magnetic resonance imaging (MRI) findings can help diagnose hibernomas, a rare benign tumor. Key MRI features include a well-defined, heterogeneous mass with low signal bands, slightly hypointense to fat on T1-weighted images.

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Last Updated: Jul 18, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Area of Science:

Radiology
Oncology
Pathology

Background:

Hibernomas are rare, benign tumors originating from brown adipose tissue.
Accurate preoperative diagnosis can guide appropriate management and avoid unnecessary interventions.

Purpose of the Study:

To characterize the preoperative magnetic resonance imaging (MRI) findings in histologically confirmed hibernomas.
To identify imaging features that aid in the differential diagnosis of hibernoma.

Main Methods:

Retrospective analysis of MRI scans (T1-weighted, STIR/fat-saturated T2-weighted, and gadolinium-enhanced T1-weighted sequences) from eight patients with hibernoma.
Assessment of lesion site, size, and signal characteristics.
Correlation with patient demographics and clinical presentation.

Main Results:

Seven of eight lesions were located in the thigh, with one superficial to the scapula.
All hibernomas appeared as well-defined, heterogeneous masses, slightly hypointense to subcutaneous fat on T1-weighted images.
Characteristic findings included prominent thin low signal bands and incomplete signal suppression on fat-saturated sequences.

Conclusions:

Preoperative MRI findings of a diffusely slightly hypointense lesion relative to surrounding subcutaneous fat should raise suspicion for hibernoma.
Recognizing these specific MRI features can improve diagnostic accuracy for hibernoma.