Related Experiment Video
Updated: Jul 18, 2026

A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury
Published on: January 5, 2015
Central cord injury: pathophysiology, management, and outcomes
James S Harrop1, Ashwini Sharan, Jonathon Ratliff
1Department of Neurosurgery, Jefferson Medical College, 909 Walnut St., 2nd Floor, Philadelphia, PA 19107, USA. James.harrop@jefferson.edu
Background Context:
Cervical spinal trauma can result in a heterogeneous collection of spinal cord injury syndromes. Acute traumatic central cord syndrome is a common category of which no uniform consensus on the etiology, pathophysiology, and treatment exists.
Purpose:
To evaluate and review potential pathophysiology, current treatment options, and management of central cord injuries.
Study Design:
Comprehensive literature review and clinical experience.
Methods:
A systematic review of Medline for articles related to central cord and spinal cord injury was conducted up to and including journal articles published in September 2005.
Conclusions:
Central cord injuries is a clinical definition which is composed of a heterogeneous population for which medical management and surgical decompression and stabilization provide improved neurologic recovery.
Related Concept Videos
Spinal Cord Injury ll: Pathophysiology
Secondary Spinal Cord Injury llI: Pathophysiology
Spinal Cord: Cross-sectional Anatomy
Gray Matter and its Components
Central to the gray matter is...
Ischemic Stroke ll: Pathophysiology
Acute Coronary Syndrome IV: Interprofessional Care
The Spinal Cord

