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Updated: Jul 18, 2026

Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection
11:44

Establishment of a Rat Model for Intrauterine Adhesions via Dual Injury: Curettage and Infection

Published on: October 3, 2025

Medicated intrauterine systems for treatment of endometriosis-associated pain

Ludovico Muzii1

  • 1Department of Obstetrics and Gynecology, Campus Bio-Medico University, Rome, Italy. l.muzii@unicampus.it

Journal of Minimally Invasive Gynecology
|November 14, 2006
PubMed

Medicated intrauterine systems (IUSs) are intrauterine devices that act by means of the local release of a medication. The levonorgestrel (LNG)-IUS is a T-shaped device that releases the progestogen LNG directly into the uterine cavity. The LNG-IUS can be used with noncontraceptive, therapeutic intent for idiopathic menorrhagia, hormonal replacement therapy in conjunction with oral or transdermal estrogens, and endometriosis or adenomyosis-associated pain. For this last indication, however, the use of the LNG-IUS is still under clinical investigation.

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