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Related Experiment Video

Updated: Jul 18, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Sclerosing mesenteritis associated with giant-cell temporal arteritis.

Mehran Howaizi¹, Akotete Kanate

¹Service de Gastroentérologie et hépatologie, Fédération médicochirurgicale des maladies de l'appareil digestif, Hôpital Simone Veil, 95602 Eaubonne, France.

European Journal of Internal Medicine

|November 14, 2006

Summary

Sclerosing mesenteritis (SM) and giant-cell arteritis (GCA) can co-occur. This case suggests considering GCA screening in patients with SM, as both conditions responded to steroids and relapsed together.

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Multimodality Diagnosis of Mesenteric Ischemia

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Last Updated: Jul 18, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Multimodality Diagnosis of Mesenteric Ischemia

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Area of Science:

Gastroenterology
Rheumatology
Vascular Medicine

Background:

Sclerosing mesenteritis (SM) is a rare benign chronic inflammatory disease of the mesentery.
Giant-cell arteritis (GCA) is a systemic vasculitis primarily affecting large and medium-sized arteries.
The co-occurrence of SM and GCA is not well-documented.

Purpose of the Study:

To report a case of simultaneous sclerosing mesenteritis and giant-cell arteritis.
To discuss the potential association between these two conditions.
To suggest a diagnostic approach for patients presenting with SM.

Main Methods:

Case report of a 72-year-old man with abdominal pain, headache, and weight loss.
Diagnostic workup included CT scan, mesenteric tissue biopsy, and temporal artery biopsy.
Treatment involved steroid therapy.

Main Results:

CT scan revealed sclerosing mesenteritis.
Mesenteric biopsy excluded malignancy.
Temporal artery biopsy confirmed giant-cell arteritis.
Both conditions responded to steroid treatment and relapsed simultaneously upon withdrawal.

Conclusions:

The association between SM and GCA, while potentially coincidental, warrants further investigation.
Screening for GCA should be considered in elderly patients diagnosed with SM, especially those exhibiting suggestive symptoms.
A temporal artery biopsy may be a valuable diagnostic tool in such cases.