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Pitfalls in paediatric appendicitis: Highlighting common clinical features of missed cases
Melanie D W Seah1, Kee-Chong Ng
1Department of Emergency Medicine, KK Women's and Children's Hospital, Singapore. melanie_SEAH@ttsh.com.sg
Insights
Pediatric appendicitis is often missed, with common symptoms like nausea, vomiting, and fever. Misdiagnoses of gastroenteritis or constipation delay critical treatment, increasing surgical complications.
Area of Science:
- Pediatric Surgery
- Emergency Medicine
- Diagnostic Accuracy
Background:
- Delayed diagnosis of pediatric appendicitis leads to increased surgical complications.
- Identifying clinical features of missed appendicitis cases is crucial for timely intervention.
Purpose of the Study:
- To identify common clinical features of pediatric appendicitis cases that were initially missed at first hospital attendance.
- To understand the diagnostic challenges and outcomes associated with delayed appendicitis diagnosis in children.
Main Methods:
- Retrospective review of case records for pediatric patients with missed appendicitis diagnoses.
- Documentation of patient presentation, investigations, initial diagnoses, and outcomes.
Main Results:
- 7% of appendicitis cases were missed over a 2-year, 5-month period, involving 39 patients.
- Common symptoms included nausea, vomiting, and fever; abdominal pain was rarely localized to the right iliac fossa (5.1%).
- Gastroenteritis (51.3%) and constipation (25.6%) were the most frequent initial misdiagnoses, leading to delayed surgery in 51.3% of discharged patients.
Conclusions:
- The absence of right lower quadrant pain does not rule out appendicitis in children.
- Gastroenteritis and constipation are significant mimics of pediatric appendicitis, necessitating a high index of suspicion.
- Avoiding wrongful discharge is critical to prevent delayed surgical intervention and associated complications.
Objective:
Missed cases of paediatric appendicitis lead to a delay in diagnosis and increased complications during the subsequent surgery. We aim to identify the common clinical features of such cases at the time of first hospital attendance.
Methods:
Case records of patients with a missed diagnosis were reviewed retrospectively, documenting the presentation, preliminary investigations, initial diagnosis and eventual outcome.
Results:
Thirty-nine patients fitted our criteria over a 2-year and 5-month period. The rate of "missed appendicitis" was 7%. The commonest symptoms and signs were that of nausea and vomiting (74.4%), abdominal pain (74.4%) and fever (61.5%). The site of abdominal pain was rarely in the right iliac fossa (5.1%). The two commonest diagnoses made at first presentation was that of gastroenteritis (51.3%) and constipation (25.6%). Twenty patients (51.3%) were initially discharged home. Compared to those initially admitted, more of those initially discharged home underwent surgery delayed beyond 24 hours from first presentation.
Conclusion:
The paucity of symptoms and signs in the right lower quadrant does not exclude appendicitis. Gastroenteritis and colic constipation are the greatest masqueraders of paediatric appendicitis. A high index of suspicion, therefore, is necessary to avoid wrongful discharge altogether.
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