Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Whooping cough: the current scene.

Meenu Singh1, Krithika Lingappan

  • 1Post Graduate Institute of Medical Education and Research, Chandigarh, India 160012. kritmeds@gmail.com

Chest
|November 14, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Echocardiographic Detection of Pulmonary Hypertension and Right Ventricular Failure in Infants with Bronchopulmonary Dysplasia: A Survey of the BPD Collaborative.

Children (Basel, Switzerland)·2026
Same author

Acrodermatitis Enteropathica Like Rash in an Infant - Can Cystic Fibrosis be the Culprit When Zinc Isn't?

Indian journal of pediatrics·2026
Same author

The importance of sex as a biological variable in pulmonary vascular research.

American journal of physiology. Lung cellular and molecular physiology·2026
Same author

Perturbation of the preterm human immune system in early life.

JCI insight·2026
Same author

Modulation of alveolar macrophages by sex as a biological variable.

American journal of physiology. Lung cellular and molecular physiology·2026
Same author

Examining the role of biologic sex on kidney outcomes in preterm neonates: A secondary analysis of the PENUT/REPAIReD study.

Pediatric nephrology (Berlin, Germany)·2026
Same journal

The effect of a two-day stay at high altitude (2500 m) on right ventricular afterload and oxygen delivery in patients with pulmonary vascular disease A randomized controlled crossover trial.

Chest·2026
Same journal

A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

Chest·2026
Same journal

Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

Chest·2026
Same journal

Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

Chest·2026
Same journal

Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

Chest·2026
Same journal

Symptom prevalence and impact on lung cancer risk in the SUMMIT study.

Chest·2026
See all related articles

Pertussis is resurging globally in adolescents and adults, posing a risk to infants. Early recognition and updated vaccination strategies are crucial for controlling this highly contagious disease.

Area of Science:

  • * Public Health
  • * Infectious Diseases
  • * Vaccinology

Background:

  • * Pertussis (whooping cough), caused by *Bordetella pertussis*, is experiencing a global resurgence.
  • * Epidemiological shifts show increased incidence in adolescents and adults in developed nations, prompting policy changes.
  • * The South East Asian region may face similar epidemiological changes, with reported outbreaks in various countries.

Purpose of the Study:

  • * To highlight the changing epidemiology of pertussis, particularly the shift towards adolescent and adult populations.
  • * To emphasize the importance of early recognition of pertussis in these age groups.
  • * To discuss the implications for vaccination policies and disease control in the South East Asian region.

Main Methods:

Related Experiment Videos

  • * Review of global pertussis epidemiology, focusing on shifts in age distribution.
  • * Analysis of clinical presentation and diagnostic challenges in adolescents and adults.
  • * Evaluation of pertussis vaccine history, including whole-cell and acellular formulations, and their efficacy and safety profiles.

    • Main Results:

    • * Pertussis incidence is increasing in adolescents and adults worldwide, despite high immunization coverage.
    • * Atypical clinical presentations in older individuals can lead to misdiagnosis.
    • * Advanced diagnostics like PCR and serology aid in later-stage disease detection when cultures are negative.
    • * Acellular pertussis vaccines are safe and effective boosters for adolescents but may be cost-prohibitive for developing regions.

    Conclusions:

    • * Adolescents and adults act as reservoirs for pertussis, endangering vulnerable infants.
    • * Revised vaccination strategies are necessary to address the changing epidemiology.
    • * The high cost of acellular pertussis vaccines may hinder widespread implementation in developing South East Asian nations.