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Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
Published on: August 8, 2025
Head and neck hemangiomas of infancy
1Department of Otolaryngology, Head and Neck Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA. macarthc@ohsu.edu
Current Opinion in Otolaryngology & Head and Neck Surgery
|November 14, 2006
Summary
Infantile hemangiomas, common benign tumors, are better understood through new markers and classification. Research identifies high-risk subtypes and guides early intervention for improved infant outcomes.
Area of Science:
- Pediatric Oncology
- Dermatology
- Developmental Biology
Background:
- Infantile hemangiomas are the most common benign tumors in infancy, occurring in about 10% of infants.
- Over half of these vascular tumors affect the head and neck region.
- Advances in understanding stem from immunohistochemical markers, associated developmental defects, and classification schemes.
Purpose of the Study:
- To review recent advancements in the understanding and management of infantile hemangiomas.
- To highlight the identification of specific markers and risk stratification for complications.
- To discuss the implications for surgical and medical intervention strategies.
Main Methods:
- Review of current literature on infantile hemangiomas.
- Analysis of immunohistochemical markers and morphologic classification.
- Identification of hemangiomas associated with developmental anomalies.
- Evaluation of studies guiding early intervention.
Main Results:
- Specific immunohistochemical markers are identified for hemangiomas across developmental and involutional phases.
- Morphologic subtypes and locations are linked to increased risk of complications.
- Associated developmental anomalies aid in identifying infants needing further investigation.
- Studies increasingly define lesions benefiting from early surgical or medical treatment.
Conclusions:
- Progress has been made in identifying markers, high-risk subtypes, and treatment approaches for infantile hemangiomas.
- Further research will enhance knowledge of treatment options, optimal surgical timing, and potential preventive strategies.
- While the exact mechanisms are not fully elucidated, clinical management is improving.
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