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The velocardiofacial syndrome in older age: dementia and autistic features
L J M Evers1, M P Vermaak, J J M Engelen
1St Anna Foundation, Centre for People with a Mental Disability, Heel, The Netherlands. revers@stanna.koraalgroep.nl
Abstract:
Velocardiofacial syndrome (VCFS) is a syndrome with a known, but variable clinical and behavioural phenotype. Most reported cases are patients of a relatively young age. The development of the behavioural phenotype and psychopathology in older patients with VCFS is less known. We present a case of a 52 year old male patient with VCFS and a deletion in chromosome band 22q11.2. He presents with typical symptoms reported in the behavioural phenotype, autistic features and an overall deteriorating process, which fulfils the DSMIV criteria for dementia.
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