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Updated: Jul 18, 2026

Laboratory Scale Production and Purification of a Therapeutic Antibody
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Laboratory Scale Production and Purification of a Therapeutic Antibody

Published on: January 24, 2017

[Technology of immunoglobulin production. I. Technological aspects of purification]

G L Volkov

    Ukrains'Kyi Biokhimichnyi Zhurnal (1999 )
    |November 15, 2006
    PubMed

    Plasma-derived intravenous immunoglobulin (IVIG) preparations have become the major plasma products on the world blood product market due to the successful application for the prophylactic prevention of infectious diseases and replacement therapy in autoimmune and inflammatory diseases. In this review classical manufacturing processes as well as new chromatographic, membrane, and mixed industrial technologies are discussed with respect to the cost and amount of the final product of high quality and virus- and prion-safety which is to be obtained.

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