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Growth pattern of childhood thyrotoxicosis: longitudinal follow-up to final height

Somchit Jaruratanasirikul1, Hutcha Sriplung

  • 1Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand. somchit.j@psu.ac.th

Journal of the Medical Association of Thailand = Chotmaihet Thangphaet
|November 15, 2006
PubMed

Insights

Children with thyrotoxicosis experienced normal growth patterns, achieving final heights greater than their genetic potential. This final height increase may be attributed to the secular trend, not the condition itself.

Area of Science:

  • Pediatric Endocrinology
  • Growth and Development
  • Thyroid Disorders

Background:

  • Thyrotoxicosis, a condition of excess thyroid hormones, can impact childhood growth.
  • Understanding the long-term growth trajectory in children with thyrotoxicosis is crucial for clinical management.

Purpose of the Study:

  • To investigate the growth patterns and final height outcomes in children diagnosed with thyrotoxicosis during prepuberty or early puberty.

Main Methods:

  • Retrospective analysis of growth data from 40 pediatric patients with thyrotoxicosis.
  • Height and weight measurements were recorded every 3-6 months and converted to standard deviation scores (SDS).

Main Results:

  • Patients were initially underweight but became relatively overweight after one year of treatment.
  • Final height SDS averaged -0.04, comparable to the general population.
  • Patients achieved an average final height 2.85 cm greater than their target height (p < 0.01).

Conclusions:

  • Childhood thyrotoxicosis does not inherently alter growth patterns compared to the general population.
  • The observed increase in final height above genetic potential may be influenced by secular trends rather than thyrotoxicosis itself.
Abstract

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