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Marie-Claude Audet1, Sonia Goulet, François Y Doré

  • 1Ecole de psychologie, Université Laval, Canada; Centre de Recherche Université Laval Robert-Giffard (CRULRG), 2601 de la Canardière, F-6500, Beauport, Québec, Canada G1J 2G3.

Behavioural Brain Research
|November 15, 2006
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Desensitization and Tachyphylaxis

Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
Several...