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Updated: Jul 18, 2026

Self-Assembly of Microtubule Tactoids
Published on: June 23, 2022
The mitotic spindle matrix: a fibro-membranous lamin connection
1Department of Embryology, Carnegie Institution of Washington and Howard Hughes Medical Institute, Baltimore, Maryland 21218, USA. zheng@ciwemb.edu
Abstract:
The mitotic spindle apparatus has attracted the attention of cell biologists for decades. Whereas the main function of this microtubule-based system is to segregate chromosomes, spindle morphogenesis and chromosome segregation must also coordinate with the segregation of the whole cell. The finding that RanGTPase stimulates the assembly of a lamin B-containing membranous matrix in mitosis(1) may provide a connection between the segregation of mitotic chromosomes and the partitioning of membrane systems during cell division.
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