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Dysgerminoma of the ovary. Cytologic, histologic and electron microscopic study of a case
K Hees1, J P de Jonge, D H von Kortzfleisch
1Department of Pathology, Municipal Hospital, Cologne, Federal Republic of Germany.
Acta Cytologica
|May 1, 1991
Abstract:
A case of ovarian dysgerminoma is reported. Both histology and cytology showed cells with distinctive anisokaryosis and large, sometimes bizarre, nucleoli as the most striking feature. A lymphocytic infiltration was present. Electron microscopy showed large convoluted nucleoli, structures resembling so-called "annulated lamellae" and glycogen particles, features that are typical of a germ-cell tumor. The cytologic, histologic and ultrastructural investigations revealed a dysgerminoma; that diagnosis was not certain on the frozen sections.