Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Wilms' tumor--histologic variation and prognosis.

W Lawler, H B Marsden, M K Palmer

    Cancer
    |September 1, 1975
    PubMed
    Summary

    Histologic analysis of Wilms' tumor revealed a classification based on tubular status significantly correlates with clinical stage and patient survival. This finding aids in predicting outcomes for pediatric kidney cancer.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comparison of the effects of different statins and doses on lipid levels in patients with diabetes: results from VOYAGER.

    Nutrition, metabolism, and cardiovascular diseases : NMCD·2012
    Same author

    Increased age, high body mass index and low HDL-C levels are related to an echolucent carotid intima-media: the METEOR study.

    Journal of internal medicine·2011
    Same author

    Manual or semi-automated edge detection of the maximal far wall common carotid intima-media thickness: a direct comparison.

    Journal of internal medicine·2011
    Same author

    C-reactive protein lowering with rosuvastatin in the METEOR study.

    Journal of internal medicine·2010
    Same author

    Intensive lipid lowering may reduce progression of carotid atherosclerosis within 12 months of treatment: the METEOR study.

    Journal of internal medicine·2009
    Same author

    A study of soft tissue sarcomas after childhood cancer in Britain.

    British journal of cancer·2007

    Area of Science:

    • Pediatric Oncology
    • Nephropathology
    • Cancer Histology

    Background:

    • Wilms' tumor is the most common pediatric kidney malignancy.
    • Accurate prognostic indicators are crucial for treatment stratification.
    • Histologic subtype can influence patient outcomes.

    Purpose of the Study:

    • To classify Wilms' tumors based on tubular status.
    • To evaluate the correlation between histologic classification and clinical parameters.
    • To determine if histologic findings predict patient survival.

    Main Methods:

    • Histologic analysis of 75 consecutive Wilms' tumor cases.
    • Development of a classification system based on tubular differentiation.
    • Comparison of histologic data with clinical stage and survival data.

    Main Results:

    • A novel classification system based on tubular status was established.
    • Histologic classification demonstrated a significant correlation with clinical stage.
    • Histologic classification was also significantly correlated with patient survival.

    Conclusions:

    • Tubular status-based histologic classification is a significant prognostic factor in Wilms' tumor.
    • This classification can aid in stratifying patients and predicting outcomes.
    • Further research into specific histologic features may refine prognostic models.

    Related Experiment Videos