Diuretic and analgesic effects of the methanol extract of Phoenix sylvestris root
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Published on: December 23, 2022
M A B Howlader1, S C Bachar, F Begum
1Department of Pharmacology & Clinical Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Abstract:
The analgesic and diuretic activities of the methanol extract of Phoenix sylvestris root on Swiss albino mice were observed. The extract showed significant (p<0.001) analgesic activity by reduction of percent inhibition of writhing induced by acetic acid (0.5% v/v) in 20.07% and 32.57% at a dose level of 150 mg/kg and 300-mg/kg body weights respectively. The methanol extract also showed diuretic effect at 1st hour of the study at 300-mg/kg and 2nd and 4th hour of the study at 150-mg/kg-body weight on swiss albino mice. The onset of diuretic effect was faster at a dose of 300-mg/kg body weights than 150 mg/kg body weight. The obtained results may give a clue for extensive phytochemical investigation of the plant for the development of herbal medicine.
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