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Particle Agglutination Method for Poliovirus Identification
Published on: April 20, 2011
Acute disseminated encephalomyelitis associated with oral polio vaccine
Kensaku Shibazaki1, Tatsufumi Murakami, Ryutaro Kushida
1Division of Neurology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki.
Abstract:
A 27-year-old woman presented with acute paresis after taking an oral polio vaccine (OPV). Deep tendon reflexes were preserved, needle electromyography showed no neurogenic changes, and there were no lesions on spine magnetic resonance imaging (MRI), suggesting that motor neurons of the spinal cord were not affected. Brain MRI showed abnormal lesions in the tegmentum of the upper pons, left cerebral peduncles, truncus of the corpus callosum, and right parietal lobe. Cerebrospinal fluid revealed mild pleocytosis. The most probable diagnosis was acute disseminated encephalomyelitis associated with OPV.
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