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Multiple intestinal lymphomatous polyposis in a Jindo dog
Da-Hee Jeong1, Sun-Hee Do, Il-Hwa Hong
1Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea.
Journal of Veterinary Science
|November 16, 2006
Summary
A canine intestinal lymphoma case presented with multiple polyps. Histopathology confirmed B-cell lymphoma, positive for CD20, indicating a rare form of canine gastrointestinal cancer.
Area of Science:
- Veterinary Pathology
- Canine Oncology
- Gastrointestinal Diseases
Background:
- Intestinal obstruction in dogs can stem from various causes, including neoplastic conditions.
- Canine lymphoma, while common, can manifest in diverse ways within the gastrointestinal tract.
Observation:
- A 5-year-old Jindo dog presented with intestinal obstruction (ileus).
- Surgical excision revealed thickened intestinal walls with multinodular masses and mucosal protuberances.
- Histopathology showed large, ovoid neoplastic cells infiltrating intestinal layers, forming polypoid masses.
Findings:
- The diagnosis was canine multiple intestinal malignant lymphomatous polyposis.
- Immunohistochemistry confirmed the neoplastic cells were of B-cell origin, expressing CD20.
Implications:
- This case highlights a rare presentation of canine gastrointestinal lymphoma.
- Accurate diagnosis through gross, histopathological, and immunohistochemical evaluation is crucial for treatment planning.
- Understanding B-cell origin aids in targeted therapeutic strategies for canine lymphoma.
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